WAGR 2018

Voici un état de l'art des recherches menées sur le syndrome de WAGR/WAGRO :

 

PAX6-Related Aniridia.

Moosajee M, Hingorani M, Moore AT.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2018.
2003 May 20 [updated 2018 Oct 18].

PMID:

20301534

Free Books & Documents

Select item 30242502

The genetic architecture of aniridia and Gillespie syndrome.

Hall HN, Williamson KA, FitzPatrick DR.

Hum Genet. 2018 Sep 22. doi: 10.1007/s00439-018-1934-8. [Epub ahead of print] Review.

PMID:

30242502

 

Select item 29572054

Nephron-sparing Surgery for Syndromic Wilms' Tumor: Robotic Approach.

Yadav P, Mahajan A, Kandpal DK, Chowdhary SK.

Urology. 2018 Jun;116:172-175. doi: 10.1016/j.urology.2018.03.003. Epub 2018 Mar 20.

PMID:

29572054

Molecular diagnostics of disorders of sexual development: an Indian survey and systems biology perspective.

Nagaraja MR, Gubbala SP, Delphine Silvia CRW, Amanchy R.

Syst Biol Reprod Med. 2018 Dec 14:1-16. doi: 10.1080/19396368.2018.1549619. [Epub ahead of print]

PMID:

30550360

Select item 305425162.

Extremely strong infiltration of WT1-specific CTLs into mouse tumor by the combination vaccine with WT1-specific CTL and helper peptides.

Nakata J, Nakajima H, Hayashibara H, Imafuku K, Morimoto S, Fujiki F, Motooka D, Okuzaki D, Hasegawa K, Hosen N, Tsuboi A, Oka Y, Kumanogoh A, Oji Y, Sugiyama H.

Oncotarget. 2018 Nov 13;9(89):36029-36038. doi: 10.18632/oncotarget.26338. eCollection 2018 Nov 13.

PMID:

30542516

Free PMC Article

Select item 305300433.

Effect of antiepileptic drug (Topiramate) and cold pressed ginger oil on testicular genes expression, sexual hormones and histopathological alterations in mice.

El Makawy AI, Ibrahim FM, Mabrouk DM, Ahmed KA, Fawzy Ramadan M.

Biomed Pharmacother. 2018 Dec 5;110:409-419. doi: 10.1016/j.biopha.2018.11.146. [Epub ahead of print]

PMID:

30530043

Free Article

 

Select item 305061334.

The clinical significance of the alternative Wilms tumor gene overexpression-hypermethylation signature in acute myeloid leukemia.

El Bordiny M, Al-Ghandour A, Abo Elwafa RA, Fayed O.

Clin Transl Oncol. 2018 Nov 30. doi: 10.1007/s12094-018-1998-x. [Epub ahead of print]

PMID:

30506133

Select item 305043745.

Embryonal Origin of Metanephric Adenoma and its Differential Diagnosis.

Sarlos DP, Banyai D, Peterfi L, Szanto A, Kovacs G.

Anticancer Res. 2018 Dec;38(12):6663-6667. doi: 10.21873/anticanres.13033.

PMID:

30504374

Select item 305166176.

Wilms Tumor of the Ovary: Review of the Literature and Report of 2 Cases.

Turashvili G, Fix DJ, Soslow RA, Park KJ.

Int J Gynecol Pathol. 2018 Dec 3. doi: 10.1097/PGP.0000000000000565. [Epub ahead of print]

PMID:

30516617

Select item 304687807.

Deletion of an intronic HIF-2α binding site suppresses hypoxia-induced WT1 expression.

Krueger K, Catanese L, Sciesielski LK, Kirschner KM, Scholz H.

Biochim Biophys Acta Gene Regul Mech. 2018 Nov 20;1862(1):71-83. doi: 10.1016/j.bbagrm.2018.11.003. [Epub ahead of print]

PMID:

30468780

Select item 304563698.

Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord.

Schnerwitzki D, Perry S, Ivanova A, Caixeta FV, Cramer P, Günther S, Weber K, Tafreshiha A, Becker L, Vargas Panesso IL, Klopstock T, Hrabe de Angelis M, Schmidt M, Kullander K, Englert C.

Life Sci Alliance. 2018 Aug 16;1(4):e201800106. doi: 10.26508/lsa.201800106. eCollection 2018 Aug.

PMID:

30456369

Free PMC Article

Select item 304512319.

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney.

Rush BM, Small SA, Stolz DB, Tan RJ.

J Vis Exp. 2018 Nov 1;(141). doi: 10.3791/58162.

PMID:

30451231

Select item 3045061410.

Differential expression of Wilms' tumour 1 gene in porcine urogenital organs during development.

Tan W, Zhang X, Wang Z, Chen Y, Wang A, Chu M, Tang B, Li Z.

Anat Histol Embryol. 2018 Nov 18. doi: 10.1111/ahe.12415. [Epub ahead of print]

PMID:

30450614

Select item 3045016011.

Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice.

Annesley CE, Rabik C, Duffield AS, Rau RE, Magoon D, Li L, Huff V, Small D, Loeb DM, Brown P.

Oncotarget. 2018 Oct 19;9(82):35313-35326. doi: 10.18632/oncotarget.26238. eCollection 2018 Oct 19.

PMID:

30450160

Free PMC Article

Select item 3043020512.

A phase I clinical study of a cocktail vaccine of Wilms' tumor 1 (WT1) HLA class I and II peptides for recurrent malignant glioma.

Tsuboi A, Hashimoto N, Fujiki F, Morimoto S, Kagawa N, Nakajima H, Hosen N, Nishida S, Nakata J, Morita S, Sakamoto J, Oji Y, Oka Y, Sugiyama H.

Cancer Immunol Immunother. 2018 Nov 14. doi: 10.1007/s00262-018-2274-1. [Epub ahead of print]

PMID:

30430205

Select item 3039594213.

Co-activation of WT1 and AP-1 proteins on WT1 gene promoter to induce WT1 gene expression in K562 cells.

Anuchapreeda S, Rungrojsakul M, Tima S, Chiampanichayakul S, Krig SR.

Cell Signal. 2019 Jan;53:339-347. doi: 10.1016/j.cellsig.2018.11.001. Epub 2018 Nov 3.

PMID:

30395942

Select item 3037412314.

WT1 expression in vessels varies with histopathological grade in tumour-bearing and control tissue from patients with breast cancer.

McGregor RJ, Chau YY, Kendall TJ, Artibani M, Hastie N, Hadoke PWF.

Br J Cancer. 2018 Dec;119(12):1508-1517. doi: 10.1038/s41416-018-0317-1. Epub 2018 Oct 30.

PMID:

30374123

Select item 3036746515.

Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation.

Kruber P, Angay O, Winkler A, Bösl MR, Kneitz S, Heinze KG, Gessler M.

Int J Cancer. 2018 Oct 27. doi: 10.1002/ijc.31952. [Epub ahead of print]

PMID:

30367465

Select item 3034492716.

Establishment of a novel platform cell line for efficient and precise evaluation of T cell receptor functional avidity.

Morimoto S, Fujiki F, Kondo K, Nakajima H, Kobayashi Y, Inatome M, Aoyama N, Nishida Y, Tsuboi A, Oka Y, Nishida S, Nakata J, Hosen N, Oji Y, Sugiyama H.

Oncotarget. 2018 Sep 25;9(75):34132-34141. doi: 10.18632/oncotarget.26139. eCollection 2018 Sep 25.

PMID:

30344927

Free PMC Article

Select item 3034492317.

Genetic and epigenetic analyses guided by high resolution whole-genome SNP array reveals a possible role of CHEK2 in Wilms tumour susceptibility.

Ciceri S, Gamba B, Corbetta P, Mondini P, Terenziani M, Catania S, Nantron M, Bianchi M, D'Angelo P, Torri F, Macciardi F, Collini P, Di Martino M, Melchionda F, Di Cataldo A, Spreafico F, Radice P, Perotti D; AIEOP study group.

Oncotarget. 2018 Sep 25;9(75):34079-34089. doi: 10.18632/oncotarget.26123. eCollection 2018 Sep 25.

PMID:

30344923

Free PMC Article

Select item 2030153418.

PAX6-Related Aniridia.

Moosajee M, Hingorani M, Moore AT.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2018.
2003 May 20 [updated 2018 Oct 18].

PMID:

20301534

Free Books & Documents

Select item 3030620219.

Phase I/II clinical trial of a Wilms' tumor 1-targeted dendritic cell vaccination-based immunotherapy in patients with advanced cancer.

Zhang W, Lu X, Cui P, Piao C, Xiao M, Liu X, Wang Y, Wu X, Liu J, Yang L.

Cancer Immunol Immunother. 2018 Oct 10. doi: 10.1007/s00262-018-2257-2. [Epub ahead of print]

PMID:

30306202

Select item 3029497220.

A 46,XX testicular disorder of sex development caused by a Wilms' tumour Factor-1 (WT1) pathogenic variant.

Gomes NL, de Paula LCP, Silva JM, Silva TE, Lerário AM, Nishi MY, Batista RL, Faria Júnior JAD, Moraes D, Costa EMF, Hemesath TP, Guaragna-Filho G, Leite JCL, Carvalho CG, Domenice S, Costa EC, Mendonca BB.

Clin Genet. 2019 Jan;95(1):172-176. doi: 10.1111/cge.13459. Epub 2018 Oct 28.

PMID:

30294972

Urinary Exosomal mRNA of WT1 as Diagnostic and Prognostic Biomarker for Diabetic Nephropathy.

Abe H, Sakurai A, Ono H, Hayashi S, Yoshimoto S, Ochi A, Ueda S, Nishimura K, Shibata E, Tamaki M, Kishi F, Kishi S, Murakami T, Nagai K, Doi T.

J Med Invest. 2018;65(3.4):208-215. doi: 10.2152/jmi.65.208.

PMID:

30282862

Free Article

Select item 3024250222.

The genetic architecture of aniridia and Gillespie syndrome.

Hall HN, Williamson KA, FitzPatrick DR.

Hum Genet. 2018 Sep 22. doi: 10.1007/s00439-018-1934-8. [Epub ahead of print] Review.

PMID:

30242502

Select item 3023095923.

Long-term survival of pancreatic cancer patients treated with multimodal therapy combined with WT1-targeted dendritic cell vaccines.

Hanada S, Tsuruta T, Haraguchi K, Okamoto M, Sugiyama H, Koido S.

Hum Vaccin Immunother. 2018 Sep 19:1-10. doi: 10.1080/21645515.2018.1524238. [Epub ahead of print]

PMID:

30230959

Select item 3022146924.

Paternally inherited WT1 mutation plus uniparental disomy of 11p may be an essential mechanism for development of WT1-mutated familial Wilms tumor.

Sato Y, Haruta M, Kaneko Y, Nakasato Y, Kurosawa H, Yoshihara S.

Pediatr Blood Cancer. 2019 Jan;66(1):e27442. doi: 10.1002/pbc.27442. Epub 2018 Sep 16. No abstract available.

PMID:

30221469

Select item 3021092425.

Co-inhibition of TIGIT, PD1, and Tim3 reverses dysfunction of Wilms tumor protein-1 (WT1)-specific CD8+ T lymphocytes after dendritic cell vaccination in gastric cancer.

Lu X, Liu J, Cui P, Liu T, Piao C, Xu X, Zhang Q, Xiao M, Liu X, Wang Y, Yang L.

Am J Cancer Res. 2018 Aug 1;8(8):1564-1575. eCollection 2018.

PMID:

30210924

Free PMC Article

Select item 3018822726.

Associations between the peripheral blood Wilms tumor gene 1 level and both bone marrow blast cells and the prognosis in patients with myelodysplastic syndrome.

Mashima K, Ikeda T, Toda Y, Ito S, Umino K, Minakata D, Nakano H, Morita K, Yamasaki R, Kawasaki Y, Sugimoto M, Ashizawa M, Yamamoto C, Fujiwara S, Hatano K, Sato K, Oh I, Ohmine K, Muroi K, Kanda Y.

Leuk Lymphoma. 2018 Sep 6:1-8. doi: 10.1080/10428194.2018.1504940. [Epub ahead of print]

PMID:

30188227

Select item 3018110427.

Role of Sequential Monitoring of WT1 Gene Expression in Patients With Acute Myeloid Leukemia for the Early Detection of Leukemia Relapse.

Mashima K, Oh I, Ikeda T, Toda Y, Ito S, Umino K, Minakata D, Nakano H, Morita K, Yamasaki R, Kawasaki Y, Sugimoto M, Yamamoto C, Ashizawa M, Fujiwara SI, Hatano K, Sato K, Omine K, Muroi K, Kanda Y.

Clin Lymphoma Myeloma Leuk. 2018 Dec;18(12):e521-e527. doi: 10.1016/j.clml.2018.07.298. Epub 2018 Aug 4.

PMID:

30181104

Select item 3017116328.

Human Pluripotent Stem Cell-Derived Kidney Model for Nephrotoxicity Studies.

Bajaj P, Rodrigues AD, Steppan CM, Engle SJ, Mathialagan S, Schroeter T.

Drug Metab Dispos. 2018 Nov;46(11):1703-1711. doi: 10.1124/dmd.118.082727. Epub 2018 Aug 31.

PMID:

30171163

Select item 3015676829.

Ancillary studies in pleural, pericardial, and peritoneal effusion cytology.

Sundling KE, Cibas ES.

Cancer Cytopathol. 2018 Aug;126 Suppl 8:590-598. doi: 10.1002/cncy.22021. Review.

PMID:

30156768

Select item 3015561730.

Molecular and epidemiologic characterization of Wilms tumor from Baghdad, Iraq.

Phelps HM, Al-Jadiry MF, Corbitt NM, Pierce JM, Li B, Wei Q, Flores RR, Correa H, Uccini S, Frangoul H, Alsaadawi AR, Al-Badri SAF, Al-Darraji AF, Al-Saeed RM, Al-Hadad SA, Lovvorn III HN.

World J Pediatr. 2018 Dec;14(6):585-593. doi: 10.1007/s12519-018-0181-3. Epub 2018 Aug 28.

PMID:

30155617

Select item 3014355931.

Podocyte-Specific Induction of Krüppel-Like Factor 15 Restores Differentiation Markers and Attenuates Kidney Injury in Proteinuric Kidney Disease.

Guo Y, Pace J, Li Z, Ma'ayan A, Wang Z, Revelo MP, Chen E, Gu X, Attalah A, Yang Y, Estrada C, Yang VW, He JC, Mallipattu SK.

J Am Soc Nephrol. 2018 Oct;29(10):2529-2545. doi: 10.1681/ASN.2018030324. Epub 2018 Aug 24.

PMID:

30143559

Select item 3013531532.

Wilms' tumor 1 drives fibroproliferation and myofibroblast transformation in severe fibrotic lung disease.

Sontake V, Kasam RK, Sinner D, Korfhagen TR, Reddy GB, White ES, Jegga AG, Madala SK.

JCI Insight. 2018 Aug 23;3(16). pii: 121252. doi: 10.1172/jci.insight.121252. [Epub ahead of print]

PMID:

30135315

Free PMC Article

Select item 3013252333.

Overexpression of Wilms' tumor 1 in skin lesions of psoriasis is associated with abnormal proliferation and apoptosis of keratinocytes.

Wu R, Liao Y, Shen W, Liu Y, Zhang J, Zheng M, Chen G, Su Y, Zhao M, Lu Q.

Mol Med Rep. 2018 Oct;18(4):3973-3982. doi: 10.3892/mmr.2018.9391. Epub 2018 Aug 16.

PMID:

30132523

Select item 3012360334.

Possible Correlation between Hypomelanosis of Ito and Wilms' Tumor.

Bello-Germino D, Chhin R, Tran T, Vasylyeva TL.

Case Rep Pediatr. 2018 Jul 16;2018:5938120. doi: 10.1155/2018/5938120. eCollection 2018.

PMID:

30123603

Free PMC Article

Select item 3010381735.

Injury-induced fetal reprogramming imparts multipotency and reparative properties to pericardial adipose stem cells.

Tang J, Wang X, Tan K, Zhu H, Zhang Y, Ouyang W, Liu X, Ding Z.

Stem Cell Res Ther. 2018 Aug 13;9(1):218. doi: 10.1186/s13287-018-0959-1.

PMID:

30103817

Free PMC Article

Select item 3008222336.

Wilms Tumor 1 Expression at Diagnosis Correlates With Genetic Abnormalities and Polymorphism But Is Not Independently Prognostic in Acute Myelogenous Leukemia: A Hokkaido Leukemia Net Study.

Hidaka D, Onozawa M, Hashiguchi J, Miyashita N, Kasahara K, Fujisawa S, Hayase E, Okada K, Shiratori S, Goto H, Sugita J, Nakagawa M, Hashimoto D, Kahata K, Endo T, Yamamoto S, Tsutsumi Y, Haseyama Y, Nagashima T, Mori A, Ota S, Sakai H, Ishihara T, Imai K, Miyagishima T, Kakinoki Y, Kurosawa M, Kobayashi H, Iwasaki H, Shimizu C, Kondo T, Teshima T.

Clin Lymphoma Myeloma Leuk. 2018 Nov;18(11):e469-e479. doi: 10.1016/j.clml.2018.07.291. Epub 2018 Jul 17.

PMID:

30082223

Select item 3006497337.

Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis.

Pronier E, Bowman RL, Ahn J, Glass J, Kandoth C, Merlinsky TR, Whitfield JT, Durham BH, Gruet A, Hanasoge Somasundara AV, Rampal R, Melnick A, Koche RP, Taylor BS, Levine RL.

Blood. 2018 Sep 20;132(12):1265-1278. doi: 10.1182/blood-2018-03-837468. Epub 2018 Jul 31.

PMID:

30064973

Free PMC Article

Select item 3005740538.

Transcription factors WT1 and p53 combined: a prognostic biomarker in ovarian cancer.

Carter JH, Deddens JA, Mueller G, Lewis TG, Dooley MK, Robillard MC, Frydl M, Duvall L, Pemberton JO, Douglass LE.

Br J Cancer. 2018 Aug;119(4):462-470. doi: 10.1038/s41416-018-0191-x. Epub 2018 Jul 30.

PMID:

30057405

Select item 3004584039.

Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination.

Akahori Y, Wang L, Yoneyama M, Seo N, Okumura S, Miyahara Y, Amaishi Y, Okamoto S, Mineno J, Ikeda H, Maki T, Fujiwara H, Akatsuka Y, Kato T, Shiku H.

Blood. 2018 Sep 13;132(11):1134-1145. doi: 10.1182/blood-2017-08-802926. Epub 2018 Jul 25.

PMID:

30045840

Free PMC Article

Select item 3003830040.

METTL3 regulates WTAP protein homeostasis.

Sorci M, Ianniello Z, Cruciani S, Larivera S, Ginistrelli LC, Capuano E, Marchioni M, Fazi F, Fatica A.

Cell Death Dis. 2018 Jul 23;9(8):796. doi: 10.1038/s41419-018-0843-z.

PMID:

30038300

Free PMC Article

Campbell de Morgan Spots (Cherry Angiomas) Show Endothelial Proliferation.

Fernandez-Flores A, Colmenero I.

Am J Dermatopathol. 2018 Dec;40(12):894-898. doi: 10.1097/DAD.0000000000001216.

PMID:

30024413

Select item 3000894442.

Prognostic significance of Wilms' tumor 1 expression in patients with pancreatic ductal adenocarcinoma.

Kanai T, Ito Z, Oji Y, Suka M, Nishida S, Takakura K, Kajihara M, Saruta M, Fujioka S, Misawa T, Akiba T, Yanagisawa H, Shimodaira S, Okamoto M, Sugiyama H, Koido S.

Oncol Lett. 2018 Aug;16(2):2682-2692. doi: 10.3892/ol.2018.8961. Epub 2018 Jun 13.

PMID:

30008944

Free PMC Article

 

Select item 3000710343.

Five-day regimen of azacitidine for lower-risk myelodysplastic syndromes (refractory anemia or refractory anemia with ringed sideroblasts): A prospective single-arm phase 2 trial.

Morita Y, Maeda Y, Yamaguchi T, Urase F, Kawata S, Hanamoto H, Tsubaki K, Ishikawa J, Shibayama H, Matsumura I, Matsuda M.

Cancer Sci. 2018 Oct;109(10):3209-3215. doi: 10.1111/cas.13739. Epub 2018 Aug 26.

PMID:

30007103

Free PMC Article

 

Select item 2999581144.

Wilms' tumor 1 (WT1) as a prognosis factor in gynecological cancers: A meta-analysis.

Lu J, Gu Y, Li Q, Zhong H, Wang X, Zheng Z, Hu W, Wen L.

Medicine (Baltimore). 2018 Jul;97(28):e11485. doi: 10.1097/MD.0000000000011485.

PMID:

29995811

Free PMC Article

 

Select item 2998076745.

Modified scanning electron microscopy reveals pathological crosstalk between endothelial cells and podocytes in a murine model of membranoproliferative glomerulonephritis.

Masum MA, Ichii O, Elewa YHA, Nakamura T, Otani Y, Hosotani M, Kon Y.

Sci Rep. 2018 Jul 6;8(1):10276. doi: 10.1038/s41598-018-28617-1.

PMID:

29980767

Free PMC Article

 

Select item 2996896246.

Convergent evolution of 11p allelic loss in multifocal Wilms tumors arising in WT1 mutation carriers.

Valind A, Wessman S, Pal N, Karlsson J, Jonson T, Sandstedt B, Gisselsson D.

Pediatr Blood Cancer. 2018 Nov;65(11):e27301. doi: 10.1002/pbc.27301. Epub 2018 Jul 3.

PMID:

29968962

 

Select item 2996706947.

A carcinogenic trigger to study the function of tumor suppressor genes in Schmidtea mediterranea.

Van Roten A, Barakat AZA, Wouters A, Tran TA, Mouton S, Noben JP, Gentile L, Smeets K.

Dis Model Mech. 2018 Aug 16;11(9). pii: dmm032573. doi: 10.1242/dmm.032573.

PMID:

29967069

Free PMC Article

 

Select item 2996320148.

Pilot study of WT1 peptide-pulsed dendritic cell vaccination with docetaxel in esophageal cancer.

Matsuda T, Takeuchi H, Sakurai T, Mayanagi S, Booka E, Fujita T, Higuchi H, Taguchi J, Hamamoto Y, Takaishi H, Kawakubo H, Okamoto M, Sunamura M, Kawakami Y, Kitagawa Y.

Oncol Lett. 2018 Jul;16(1):1348-1356. doi: 10.3892/ol.2018.8734. Epub 2018 May 17.

PMID:

29963201

Free PMC Article

 

Select item 2995864149.

Description of mutation spectrum and polymorphism of Wilms' tumor 1 (WT1) gene in hypospadias patients in the Indonesian population.

Diposarosa R, Pamungkas KO, Sribudiani Y, Herman H, Suciati LP, Rahayu NS, Effendy SH.

J Pediatr Urol. 2018 Jun;14(3):237.e1-237.e7. doi: 10.1016/j.jpurol.2017.11.021. Epub 2018 Jan 31.

PMID:

29958641

 

Select item 2995398050.

Repression of WT1-Mediated LEF1 Transcription by Mangiferin Governs β-Catenin-Independent Wnt Signalling Inactivation in Hepatocellular Carcinoma.

Tan HY, Wang N, Li S, Hong M, Guo W, Man K, Cheng CS, Chen Z, Feng Y.

Cell Physiol Biochem. 2018;47(5):1819-1834. doi: 10.1159/000491063. Epub 2018 Jun 28.

PMID:

29953980

Free Article

 

Select item 2993306951.

Outcomes of Measurable Residual Disease in Pediatric Acute Myeloid Leukemia before and after Hematopoietic Stem Cell Transplant: Validation of Difference from Normal Flow Cytometry with Chimerism Studies and Wilms Tumor 1 Gene Expression.

Jacobsohn DA, Loken MR, Fei M, Adams A, Brodersen LE, Logan BR, Ahn KW, Shaw BE, Kletzel M, Olszewski M, Khan S, Meshinchi S, Keating A, Harris A, Teira P, Duerst RE, Margossian SP, Martin PL, Petrovic A, Dvorak CC, Nemecek ER, Boyer MW, Chen AR, Davis JH, Shenoy S, Savasan S, Hudspeth MP, Adams RH, Lewis VA, Kheradpour A, Kasow KA, Gillio AP, Haight AE, Bhatia M, Bambach BJ, Haines HL, Quigg TC, Greiner RJ, Talano JM, Delgado DC, Cheerva A, Gowda M, Ahuja S, Ozkaynak M, Mitchell D, Schultz KR, Fry TJ, Loeb DM, Pulsipher MA.

Biol Blood Marrow Transplant. 2018 Oct;24(10):2040-2046. doi: 10.1016/j.bbmt.2018.06.010. Epub 2018 Jun 19.

PMID:

29933069

 

Select item 2993241952.

H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers.

Fang D, Gan H, Cheng L, Lee JH, Zhou H, Sarkaria JN, Daniels DJ, Zhang Z.

Elife. 2018 Jun 22;7. pii: e36696. doi: 10.7554/eLife.36696.

PMID:

29932419

Free PMC Article

 

Select item 2985116553.

TGF-β1 Alters DNA Methylation Levels in Promoter and Enhancer Regions of the WT1 Gene in Human Podocytes.

Hamatani H, Sakairi T, Ikeuchi H, Kaneko Y, Maeshima A, Nojima Y, Hiromura K.

Nephrology (Carlton). 2018 May 30. doi: 10.1111/nep.13411. [Epub ahead of print]

PMID:

29851165

 

Select item 2980510954.

Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response.

Ueda N, Uemura Y, Zhang R, Kitayama S, Iriguchi S, Kawai Y, Yasui Y, Tatsumi M, Ueda T, Liu TY, Mizoro Y, Okada C, Watanabe A, Nakanishi M, Senju S, Nishimura Y, Kuzushima K, Kiyoi H, Naoe T, Kaneko S.

Stem Cell Reports. 2018 Jun 5;10(6):1935-1946. doi: 10.1016/j.stemcr.2018.04.025. Epub 2018 May 24.

PMID:

29805109

Free PMC Article

 

Select item 2980191655.

Leukodystrophy with disorders of sex development due to WT1 mutations.

Souza PVS, Badia BML, Silva LHL, Teixeira CAC, Seneor DD, Marin VDGB, Farias IB, Dias RB, Oliveira ASB, Pinto WBVR.

J Neurol Sci. 2018 Jul 15;390:94-98. doi: 10.1016/j.jns.2018.04.020. Epub 2018 Apr 13.

PMID:

29801916

 

Select item 2979026456.

Immune responses against tumour-associated antigen-derived cytotoxic T lymphocyte epitopes in cholangiocarcinoma patients.

Kida A, Mizukoshi E, Tamai T, Terashima T, Kitahara M, Arai K, Yamashita T, Fushimi K, Honda M, Kaneko S.

Liver Int. 2018 Nov;38(11):2040-2050. doi: 10.1111/liv.13885. Epub 2018 Jul 18.

PMID:

29790264

 

Select item 2978938157.

WT1-Expressing Interneurons Regulate Left-Right Alternation during Mammalian Locomotor Activity.

Haque F, Rancic V, Zhang W, Clugston R, Ballanyi K, Gosgnach S.

J Neurosci. 2018 Jun 20;38(25):5666-5676. doi: 10.1523/JNEUROSCI.0328-18.2018. Epub 2018 May 22.

PMID:

29789381

Free Article

 

Select item 2975383858.

Wilms' Tumor 1 Gene Expression Using a Standardized European LeukemiaNet-Certified Assay Compared to Other Methods for Detection of Minimal Residual Disease in Myelodysplastic Syndrome and Acute Myelogenous Leukemia after Allogeneic Blood Stem Cell Transplantation.

Rautenberg C, Pechtel S, Hildebrandt B, Betz B, Dienst A, Nachtkamp K, Kondakci M, Geyh S, Wieczorek D, Haas R, Germing U, Kobbe G, Schroeder T.

Biol Blood Marrow Transplant. 2018 Nov;24(11):2337-2343. doi: 10.1016/j.bbmt.2018.05.011. Epub 2018 May 16.

PMID:

29753838

 

Select item 2974314359.

The Wilms' tumour 1 gene as a factor in non-syndromic hypospadias: evidence and controversy.

Buglyó G, Beyer D, Biró S, Oláh É.

Pathology. 2018 Jun;50(4):377-381. doi: 10.1016/j.pathol.2017.12.341. Epub 2018 May 7. Review.

PMID:

29743143

 

Select item 2973910960.

A Proposed Kinetic Model for the Diagnostic and Prognostic Value of WT1 and p53 in Acute Myeloid Leukemia.

Bani-Ahmad MA, Al-Sweedan SA, Al-Asseiri MA, Alkhatib AJ.

Clin Lab. 2018 Mar 1;64(3):357-363. doi: 10.7754/Clin.Lab.2017.170915.

PMID:

29739109

 

PRAME peptide-specific CD8+ T cells represent the predominant response against leukemia-associated antigens in healthy individuals.

Matko S, Manderla J, Bonsack M, Schmitz M, Bornhauser M, Tonn T, Odendahl M.

Eur J Immunol. 2018 Aug;48(8):1400-1411. doi: 10.1002/eji.201747399. Epub 2018 Jul 8.

PMID:

29738081

 

Select item 2970862562.

Role of the Wilms' tumor suppressor gene Wt1 in pancreatic development.

Ariza L, Cañete A, Rojas A, Muñoz-Chápuli R, Carmona R.

Dev Dyn. 2018 Jul;247(7):924-933. doi: 10.1002/dvdy.24636. Epub 2018 May 30.

PMID:

29708625

 

Select item 2966307163.

Cyclosporine A responsive congenital nephrotic syndrome with single heterozygous variants in NPHS1, NPHS2, and PLCE1.

Eichinger A, Ponsel S, Bergmann C, Günthner R, Hoefele J, Amann K, Lange-Sperandio B.

Pediatr Nephrol. 2018 Jul;33(7):1269-1272. doi: 10.1007/s00467-018-3961-z. Epub 2018 Apr 16.

PMID:

29663071

 

Select item 2966263764.

The Wilms' tumor gene-1 is a prognostic factor in myelodysplastic syndrome: a meta analysis.

Jiang Y, Liu L, Wang J, Cao Z, Zhao Z.

Oncotarget. 2017 Dec 27;9(22):16205-16212. doi: 10.18632/oncotarget.23671. eCollection 2018 Mar 23.

PMID:

29662637

Free PMC Article

 

Select item 2965896665.

Methylation in the promoter regions of WT1, NKX6-1 and DBC1 genes in cervical cancer tissues of Uygur women in Xinjiang.

Wu D, Zhang J, Fan P, Li H, Li D, Pan H, He H, Ren X, Pan Z, Shao R, Pan Z.

Genet Mol Biol. 2018 Jan-Mar;41(1):9-17. doi: 10.1590/1678-4685-GMB-2016-0146.

PMID:

29658966

Free PMC Article

 

Select item 2962675266.

Efficacy of ONC201 in Desmoplastic Small Round Cell Tumor.

Hayes-Jordan AA, Ma X, Menegaz BA, Lamhamedi-Cherradi SE, Kingsley CV, Benson JA, Camacho PE, Ludwig JA, Lockworth CR, Garcia GE, Craig SL.

Neoplasia. 2018 May;20(5):524-532. doi: 10.1016/j.neo.2018.02.006. Epub 2018 Apr 5.

PMID:

29626752

Free PMC Article

 

Select item 2962327567.

Wilms' Tumor Protein 1 and Enzymatic Oxidation of 5-Methylcytosine in Brain Tumors: Potential Perspectives.

Ramsawhook A, Ruzov A, Coyle B.

Front Cell Dev Biol. 2018 Mar 22;6:26. doi: 10.3389/fcell.2018.00026. eCollection 2018. Review.

PMID:

29623275

Free PMC Article

 

Select item 2961017868.

Proximal Hypospadias and a Novel WT1 Variant: When Should Genetic Testing Be Considered?

Dabrowski E, Armstrong AE, Leeth E, Johnson E, Cheng E, Gosiengfiao Y, Finlayson C.

Pediatrics. 2018 Apr;141(Suppl 5):S491-S495. doi: 10.1542/peds.2017-0230.

PMID:

29610178

 

Select item 2959934369.

Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors.

Hirabayashi K, Yanagisawa R, Saito S, Higuchi Y, Koya T, Sano K, Koido S, Okamoto M, Sugiyama H, Nakazawa Y, Shimodaira S.

Anticancer Res. 2018 Apr;38(4):2227-2234.

PMID:

29599343

 

Select item 2959934270.

WT1-pulsed Dendritic Cell Vaccine Combined with Chemotherapy for Resected Pancreatic Cancer in a Phase I Study.

Yanagisawa R, Koizumi T, Koya T, Sano K, Koido S, Nagai K, Kobayashi M, Okamoto M, Sugiyama H, Shimodaira S.

Anticancer Res. 2018 Apr;38(4):2217-2225.

PMID:

29599342

 

Select item 2958905371.

Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells.

Pons M, Reichardt CM, Hennig D, Nathan A, Kiweler N, Stocking C, Wichmann C, Christmann M, Butter F, Reichardt S, Schneider G, Heinzel T, Englert C, Hartkamp J, Krämer OH, Mahendrarajah N.

Arch Toxicol. 2018 Jun;92(6):2119-2135. doi: 10.1007/s00204-018-2202-3. Epub 2018 Mar 27.

PMID:

29589053

 

Select item 2956028072.

Micro RNAs are involved in activation of epicardium during zebrafish heart regeneration.

Ceci M, Carlantoni C, Missinato MA, Bonvissuto D, Di Giacomo B, Contu R, Romano N.

Cell Death Discov. 2018 Mar 12;4:41. doi: 10.1038/s41420-018-0041-x. eCollection 2018.

PMID:

29560280

Free PMC Article

 

Select item 2954286873.

Chemotherapy and terminal skeletal muscle differentiation in WT1-mutant Wilms tumors.

Royer-Pokora B, Beier M, Brandt A, Duhme C, Busch M, de Torres C, Royer HD, Mora J.

Cancer Med. 2018 Apr;7(4):1359-1368. doi: 10.1002/cam4.1379. Epub 2018 Mar 15.

PMID:

29542868

Free PMC Article

 

Select item 2954123674.

Differential sensitization of two human colon cancer cell lines to the antitumor effects of irinotecan combined with 5-aza-2'-deoxycytidine.

Hakata S, Terashima J, Shimoyama Y, Okada K, Fujioka S, Ito E, Habano W, Ozawa S.

Oncol Lett. 2018 Apr;15(4):4641-4648. doi: 10.3892/ol.2018.7883. Epub 2018 Jan 26.

PMID:

29541236

Free PMC Article

 

Select item 2945223075.

A regulatory circuitry between miR-193a/miR-600 and WT1 enhances leukemogenesis in acute myeloid leukemia.

Li H, Xing C, Zhou B, Ye H, Feng J, Wu J, Gao S.

Exp Hematol. 2018 May;61:59-68.e5. doi: 10.1016/j.exphem.2018.02.001. Epub 2018 Feb 13.

PMID:

29452230

 

Select item 2944557176.

Immunoreactivity of Wilms tumor 1 (WT1) as an additional evidence supporting hemangiomatous rather than inflammatory origin in the etiopathogenesis of angiolymphoid hyperplasia with eosinophilia.

Tokat F, Lehman JS, Sezer E, Cetin ED, Ince U, Durmaz EO.

Dermatol Pract Concept. 2018 Jan 31;8(1):28-32. doi: 10.5826/dpc.0801a06. eCollection 2018 Jan.

PMID:

29445571

Free PMC Article

 

Select item 2943472477.

Combined usage of Wilms' tumor gene quantitative analysis and multiparameter flow cytometry for minimal residual disease monitoring of acute myeloid leukemia patients after allogeneic hematopoietic stem cells transplantation.

Hao Y, Cheng Y, Wu Q, Zhang A, Jiang X, Xu X.

Exp Ther Med. 2018 Feb;15(2):1403-1409. doi: 10.3892/etm.2017.5547. Epub 2017 Nov 23.

PMID:

29434724

Free PMC Article

 

Select item 2942305678.

Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia.

Sodaro G, Cesaro E, Montano G, Blasio G, Fiorentino F, Romano S, Jacquel A, Aurberger P, Costanzo P.

Oncotarget. 2017 Dec 15;9(3):3417-3431. doi: 10.18632/oncotarget.23283. eCollection 2018 Jan 9.

PMID:

29423056

Free PMC Article

 

Select item 2941482579.

Wilms' Tumor 1 Overexpression in Granulosa Cells Is Associated with Polycystic Ovaries in Polycystic Ovary Syndrome Patients.

Wang Q, Huang T, Shu X, Zhao SG, Liang Y, Muhammad T, Gao F, Zhao H, Liu HB.

Gynecol Obstet Invest. 2018;83(3):241-246. doi: 10.1159/000486784. Epub 2018 Feb 7.

PMID:

29414825

 

Select item 2940718480.

Prognostic significance of The Wilms' Tumor-1 (WT1) rs16754 polymorphism in acute myeloid leukemia.

Petiti J, Rosso V, Lo Iacono M, Calabrese C, Signorino E, Gaidano V, Berger M, Saglio G, Cilloni D.

Leuk Res. 2018 Apr;67:6-11. doi: 10.1016/j.leukres.2018.01.016. Epub 2018 Feb 5.

PMID:

29407184

Activation of podocyte Notch mediates early Wt1 glomerulopathy.

Asfahani RI, Tahoun MM, Miller-Hodges EV, Bellerby J, Virasami AK, Sampson RD, Moulding D, Sebire NJ, Hohenstein P, Scambler PJ, Waters AM.

Kidney Int. 2018 Apr;93(4):903-920. doi: 10.1016/j.kint.2017.11.014. Epub 2018 Feb 2.

PMID:

29398135

Free PMC Article

 

Select item 2938619582.

Phase 2 trial of a multivalent WT1 peptide vaccine (galinpepimut-S) in acute myeloid leukemia.

Maslak PG, Dao T, Bernal Y, Chanel SM, Zhang R, Frattini M, Rosenblat T, Jurcic JG, Brentjens RJ, Arcila ME, Rampal R, Park JH, Douer D, Katz L, Sarlis N, Tallman MS, Scheinberg DA.

Blood Adv. 2018 Feb 13;2(3):224-234. doi: 10.1182/bloodadvances.2017014175.

PMID:

29386195

Free PMC Article

 

Select item 2937500783.

Recognition mechanism of Wilms' tumour suppressor protein and DNA triplets: insights from molecular dynamics simulation and free energy analysis.

Zhang LF, Zheng QC, Zhang HX.

J Biomol Struct Dyn. 2018 Feb 12:1-14. doi: 10.1080/07391102.2018.1433066. [Epub ahead of print]

PMID:

29375007

 

Select item 2935980084.

WT1 mRNA level reflects disease changes and progression of myelodysplastic syndromes patients with 'stable disease'.

Du X, Geng S, Weng J, Deng C, Lu Z, Li M, Wu P, Lai P.

Br J Haematol. 2018 Jan 23. doi: 10.1111/bjh.15098. [Epub ahead of print] No abstract available.

PMID:

29359800

 

Select item 2935817385.

Combination Gemcitabine and WT1 Peptide Vaccination Improves Progression-Free Survival in Advanced Pancreatic Ductal Adenocarcinoma: A Phase II Randomized Study.

Nishida S, Ishikawa T, Egawa S, Koido S, Yanagimoto H, Ishii J, Kanno Y, Kokura S, Yasuda H, Oba MS, Sato M, Morimoto S, Fujiki F, Eguchi H, Nagano H, Kumanogoh A, Unno M, Kon M, Shimada H, Ito K, Homma S, Oka Y, Morita S, Sugiyama H.

Cancer Immunol Res. 2018 Jan 22. doi: 10.1158/2326-6066.CIR-17-0386. [Epub ahead of print]

PMID:

29358173

 

Select item 2935741986.

Modulation of apolipoprotein L1-microRNA-193a axis prevents podocyte dedifferentiation in high-glucose milieu.

Mishra A, Ayasolla K, Kumar V, Lan X, Vashistha H, Aslam R, Hussain A, Chowdhary S, Marashi Shoshtari S, Paliwal N, Popik W, Saleem MA, Malhotra A, Meggs LG, Skorecki K, Singhal PC.

Am J Physiol Renal Physiol. 2018 May 1;314(5):F832-F843. doi: 10.1152/ajprenal.00541.2017. Epub 2018 Jan 10.

PMID:

29357419

 

Select item 2932078387.

WT1 Gene Mutation, p.R462W, in a 46,XY DSD Patient from Egypt with Gonadoblastoma and Review of the Literature.

Mazen I, Hassan H, Kamel A, Mekkawy M, McElreavey K, Essawi M.

Sex Dev. 2017;11(5-6):280-283. doi: 10.1159/000485394. Epub 2018 Jan 11. Review.

PMID:

29320783

 

Select item 2929405888.

Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites.

Wang D, Horton JR, Zheng Y, Blumenthal RM, Zhang X, Cheng X.

Nucleic Acids Res. 2018 May 4;46(8):3864-3877. doi: 10.1093/nar/gkx1274.

PMID:

29294058

Free PMC Article

 

Select item 2929221089.

Identification of a novel CTR9 germline mutation in a family with Wilms tumor.

Martins AG, Pinto AT, Domingues R, Cavaco BM.

Eur J Med Genet. 2018 May;61(5):294-299. doi: 10.1016/j.ejmg.2017.12.010. Epub 2017 Dec 29.

PMID:

29292210

 

Select item 2925314490.

Polymorphisms in the Wilms Tumor Gene Are Associated With Interindividual Variations in Rubella Virus-Specific Cellular Immunity After Measles-Mumps-Rubella II Vaccination.

Voigt EA, Haralambieva IH, Larrabee BL, Kennedy RB, Ovsyannikova IG, Schaid DJ, Poland GA.

J Infect Dis. 2018 Jan 30;217(4):560-566. doi: 10.1093/infdis/jix538.

PMID:

29253144

 

Select item 2924749491.

Podocyte and endothelial cell injury lead to nephrotic syndrome in proliferative lupus nephritis.

Nawata A, Hisano S, Shimajiri S, Wang KY, Tanaka Y, Nakayama T.

Histopathology. 2018 Jun;72(7):1084-1092. doi: 10.1111/his.13454. Epub 2018 Mar 14.

PMID:

29247494

 

Select item 2924025892.

DNA and RNA binding by the Wilms' tumour gene 1 (WT1) protein +KTS and -KTS isoforms-From initial observations to recent global genomic analyses.

Ullmark T, Montano G, Gullberg U.

Eur J Haematol. 2018 Mar;100(3):229-240. doi: 10.1111/ejh.13010. Epub 2018 Jan 10. Review.

PMID:

29240258

 

Select item 2917025493.

WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia.

Bordin F, Piovan E, Masiero E, Ambesi-Impiombato A, Minuzzo S, Bertorelle R, Sacchetto V, Pilotto G, Basso G, Zanovello P, Amadori A, Tosello V.

Haematologica. 2018 Feb;103(2):266-277. doi: 10.3324/haematol.2017.170431. Epub 2017 Nov 23.

PMID:

29170254

Free PMC Article

 

Select item 2899404194.

Quantification of Wilms' tumor 1 mRNA by digital polymerase chain reaction.

Koizumi Y, Furuya D, Endo T, Asanuma K, Yanagihara N, Takahashi S.

Int J Hematol. 2018 Feb;107(2):230-234. doi: 10.1007/s12185-017-2336-8. Epub 2017 Oct 9.

PMID:

28994041

 

Select item 2898076695.

Cancer-related mRNA expression analysis using a novel flow cytometry-based assay.

Depreter B, Philippé J, Meul M, Denys B, Vandepoele K, De Moerloose B, Lammens T.

Cytometry B Clin Cytom. 2018 Jul;94(4):565-575. doi: 10.1002/cyto.b.21593. Epub 2017 Nov 2. Review.

PMID:

28980766

 

Select item 2893061096.

RPS6KA4/MIR1237 and AURKC promoter regions are differentially methylated in Wilms' tumor.

Pereira HS, Soares Lima SC, de Faria PS, Cardoso LC, Seuanez HN.

Front Biosci (Elite Ed). 2018 Jan 1;10:143-154.

PMID:

28930610

 

Select item 2857396097.

Sensitive detection of rare antigen-specific T cells directed against Wilms' tumor 1 by FluoroSpot assay.

Danielzik T, Koldehoff M, Buttkereit U, Beelen DW, Horn PA, Lindemann M.

Leuk Lymphoma. 2018 Feb;59(2):490-492. doi: 10.1080/10428194.2017.1330955. Epub 2017 Jun 2. No abstract available.

PMID:

28573960

 

Select item 2854279398.

The genetic factors contributing to the development of Wilm's tumor and their clinical utility in its diagnosis and prognosis.

Bahrami A, Joodi M, Maftooh M, Ferns GA, M Ahmadi M, Hassanian SM, Avan A.

J Cell Physiol. 2018 Apr;233(4):2882-2888. doi: 10.1002/jcp.26021. Epub 2017 Jul 4. Review.

PMID:

28542793

Select item 2839556699.

WT1 protein is cleaved by caspase-3 in apoptotic leukemic cells.

Ruan J, Gao S, Yang J, Li H, Huang H, Zheng X.

Leuk Lymphoma. 2018 Jan;59(1):162-170. doi: 10.1080/10428194.2017.1312368. Epub 2017 Apr 10.

PMID:

28395566

Select item 27181332100.

BCR-ABL-specific CD4+ T-helper cells promote the priming of antigen-specific cytotoxic T cells via dendritic cells.

Ueda N, Zhang R, Tatsumi M, Liu TY, Kitayama S, Yasui Y, Sugai S, Iwama T, Senju S, Okada S, Nakatsura T, Kuzushima K, Kiyoi H, Naoe T, Kaneko S, Uemura Y.

Cell Mol Immunol. 2018 Jan;15(1):15-26. doi: 10.1038/cmi.2016.7. Epub 2016 May 15.

PMID:

27181332

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